产品货号：
Z35516
中文名称：
NBS1/NBN抗体
英文名称：
Anti-NBS1/NBN Antibody (Clone#5D7A1)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-NBS1/NBN Antibody (Clone#5D7A1) |
| 指标别名 | AT V1;AT V2;ATV;NBN;NBS;NBS1;nibrin;P95 |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,ICC/IF,FCM |
| 基因名称 | NBN |
| 克隆号 | 5D7A1 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG2a |
| 免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human p95 NBS1 (714-745aa RKNTELEEWLRQEMEVQNQHAKEESLADDLFR),different from the related mouse sequence by three amino acids,and from the related rat sequence by five amino acids. |
| 实际分子量 | 95KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | protein G purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | p95 NBS1,also known as NBN or Nibrin,is a protein which in humans is encoded by the NBN gene.Nibrin is a protein associated with the repair of double strand breaks (DSBs) which pose serious damage to a genome.It is a 754 amino acid protein identified as a member of the NBS1/hMre11/RAD50(N/M/R,more commonly referred to asMRN) double strand DNA break repair complex.This complex recognizes DNA damage and rapidly relocates to DSB sites and forms nuclear foci.It also has a role in regulation of N/M/R (MRN) protein complex activity which includes end-processing of both physiological and mutagenic DNA double strand breaks (DSBs). |
| Uniprot ID | O60934 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (ZN1928) for Western blot,and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (ZN1866) for IHC(P) and ICC. |
| 基因名全称 | nibrin |
| 蛋白名全称 | Nibrin |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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